Breakthrough results in developing an oral insulin tablet

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Dec 1, 2020
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A team of University of British Columbia researchers... ...have discovered that insulin from the latest version of their oral tablets is absorbed by rats in the same way that injected insulin is.
"These exciting results show that we are on the right track in developing an insulin formulation that will no longer need to be injected before every meal, improving the quality of life, as well as mental health, of more than nine million type 1 diabetics around the world," says professor Dr. Anubhav Pratap-Singh...

According to Dr. Alberto Baldelli, a senior fellow in Dr. Pratap-Singh's lab, they are now seeing nearly 100 percent of the insulin from their tablets go straight into the liver. In previous attempts to develop a drinkable insulin, most of the insulin would accumulate in the stomach.

"Even after two hours of delivery, we did not find any insulin in the stomachs of the rats we tested. It was all in the liver and this is the ideal target for insulin—it's really what we wanted to see," says Yigong Guo, first author of the study and a Ph.D. candidate working closely on the project.


As Owen Wilson would say... Wow
 
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Did you know that the original patent was sold by Banting and Macleod to the University of Toronto for $1.00 with an accompanying letter stating:
"The patent would not be used for any other purpose than to prevent the taking out of a patent by other persons. When the details of the method of preparation are published anyone would be free to prepare the extract, but no one could secure a profitable monopoly."

 
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